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, 10 30% , , . 3 15 % (American Journal of Hospital Pharmacy, July 1992).

30-50% .

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40 44 - . , , , (JAMA, September, 1997).

: , , , , , , , - , . : WWW- (), (), , CD ROM ONLINE.

, , , , , "" . ONLINE , - , . ONLINE , Dialog, STN, Data-Star, Telesystemes-Questel . , , .

, , , , -, , , , , , - (), . , , .

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, . , . , , PubMed MEDLINE "See Related Articles", , , . "" .

, . , 20% (?) . , , 1998 . " " , , .

, Prous Science, Derwent, PJB Publications, ., (, US Food and Drug Administration, National Library of Medicine, ..), (United States Pharmacopeia, Alzheimer's Association, International Federation of Pharmaceutical Manufacturers Associations, .), - (Merck & Co. Inc., Roche, Glaxo Wellcome Inc. .), , (, Capnet Gateway Online Services), .

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, , (Prouse Science, PJB Publications, ..) , , ( - $3000-$20000). .

, , , , . (, CD ROM, ONLINE), . , , WWW-, "" , , .

, , (F) - (Free); - (E) - (Expensive); , - (F) (E).

World Health Organization (F) (E).
http://www.who.ch/programmes/dap/DAP_Homepage.html
.
, 1977 , . , 6640 . , , .

USP PHARMACOPEIA (F) (E).
http://www.usp.org/did/index.htm
.
, , . 11000 . " ", , , , 750 . . , . " ", , , . , .

MEDLINE (F).
http://www.ncbi.nlm.nih.gov/PubMed
.
9 MEDLINE Pre-MEDLINE, on-line . , 4 - , , . " " (clinical alerts) - , , . , .., .

FDA - DRUGS INFORMATION (F).
http://www.fda.gov/cder/drug.htm
(FDA).
, FDA. , , 1991-1996 .. , , 06.01.98 . (Approved Drug Products with Therapeutic Equivalence Evaluations - Cumulative Supplement-9). , . 1 1969 . , . FDA . "" (http://www.fda.gov/) , , , , , , () .

The European Agency for the Evaluation of Medicinal Products (F).
http://www.eudra.org/
.
, , , . : EudraLEX - ; EudraMAT - EudraWATCH - ; . ECPHIN ECDIN - , , 120000 . , .

MDL Information Systems (E).
http://www.mdli.com
MDL Information Systems Inc. (MDL), . ISIS (Integrated Scientific Information System) 80% , . ISIS : Prous Science, PJB Publications, Derwent . , ISIS ( , ). , MDL: MDDR MDL Drug Data Report) - 80000 ; CMC (Comprehensive Medicinal Chemistry), 8000 ; Metabolite - ; OHS MSDS (Occupational Health & Safety: Material Safety Data Sheets)- , ). CD ROM ISIS. - MDL : . 095 246-33-80; E-mail: vvp@ibmh.msk.su

Prous Science (F) (E).
http://www.prous.es
Prous Science Publishers.
, , CD ROM ONLINE. Daily Essentials (-, , , ..). . , , , .; - 1 .

" ". :
1) ;
2) ;
3) ;
4) , .
, , 1997 . " " (Repaglinide, Prandin[TM]; NovoNorm[R] ). FDA II , . - , . , Novo Nordisk Boehringer Ingelheim. . , , .

Prous Science , CD ROM. : Trilogy - Drug Data Report, Drugs of the Future Drug News and Perspectives; Cipsline - 30000 , Drug Data Report Drugs of the Future; NME Express - , (New Molecular Entities); MDDR (. ). ISIS.

STN International (Europe) (E).
http://www.fiz-karlsruhe.de
FIZ-Karlsruhe.
ONLINE STN International. , DRUGLAUNCH - , 1982 . ; DRUGMONOG DRUGMONOG2 - , IMS International ( DRUGLAUNCH); DRUGNL - , IMS 1991 . ; DRUGPAT - , IMS 1987 . ; DRUGUPDATES , IMS 1987 . ; PHAR - , Pharmaprojects; DDFU/DRUGU - , Derwent 1983 . ; AIDSLINE - 1980 ; . DDFU, EMBASE, NAPRALERT . STN International 200 . STN- ... (http://www.ioc.ac.ru/; . 095 135-87-82; E-mail: khutor@ioc.ac.ru).

The Investigational Drugs Database (IDdb) (E).
http://www.current-science-group.com/cd/products.htm#idd
Current Drugs Ltd.
, (R & D). , , ; ; ; ; . "" , IDdb. : , , , , . Embase Alert. .

RxList - The Internet Drug Index (E).
http://www.rxlist.com
Neil Sandow, Pharm.D., "Automated Technologies".
, . 4000 . RxList-, , , .. 200 , 1995 1996 .., 2/3 .

PJB Publications (E).
http://www.pjbpubs.co.uk/
PJB Publications, Ltd. (UK)
Pharmaprojects, 20000 . Pharmastructures, 10000 , . ISIS CD ROM .

PharmaSource (E).
Chapman & Hall CD ROM.
http://epd.chapmanhall.com
30000 . Physicians Desk Reference, .

DRUG-REAX System: Drug Interactions (E).
CD ROM MICROMEDEX.
http://www.mdx.com
, , , ; ; , .

Doctor's Guide to the Internet (F).
http://www.docguide.com
P\S\L Consulting Group Inc.
, .., . .

Adverse Drug Reactions (E).
http://www.oup.co.uk/jnls/list/drugsj
Oxford University Press.
, Adverse Drug Reactions and Toxicological Reviews. .

PharmWeb (E).
http://www.pharmweb.net
PharmWeb.
, ; .

Pharmaceutical Online (E).
http://www.pharmaceuticalonline.com/assocevents.html
Pharmaceutical Online, M.McNulty M.Hagan 1997 . : 1) , , ; 2) , , Pharmaceutical Online.

.

Internet Self-Assessment in Pharmacology (F).
http://www-users.cs.umn.edu/~isap/intro.html
. Len Lichtblau . (Department of Pharmacology, University of Minnesota Medical School).

WWW- : , , , , . 300 , 184 . ( ).

16 18 , "-500" 1996 - , " " ( , 14, 1997 .). , .

Merck & Co. Inc.	http://www.merck.com
Roche	http://www.roche.com
Glaxo Wellcome Inc.	http://www.glaxowellcome.com
Pfizer	http://www.pfizer.com
Novartis (formed by the merger of Ciba-Geigy and Sandoz)	http://www.novartis.com
American Home Products	http://www.ahp.com
Lilly (Eli)	http://www.lilly.com
SmithKline Beecham	http://www.sb.com
Astra AB	http://www.astra.com
Zeneca Pharmaceuticals	http://www.zeneca.com
Schering-Plough	http://www.sch-plough.com
Pharmacia & Upjohn	http://www.pharmacia.se/ns3index.html
Amgen	http://wwwext.Amgen.com
Takeda Chemical Industries	http://www.medic.mie-u.ac.jp/takeda
Sankyo	http://www.sankyo-pharma.com
Taisho Pharmaceutical	http://www.iijnet.or.jp/TAISHO
Yamanouchi Pharmaceutical	http://www.yamanouchi.co.jp/eg

:
http://www.pharmweb.net/pwmirror/pw9/ifpma

, , . , , (, .); MEDWEB, Emory University Health Sciences Center Library (http://www.gen.emory.edu/medweb/medweb.pharmacy.html) 200 ; , MICROMEDEX CD ROM; .. .. . " " ( , 1997, 5, .83-88).

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